Browse Our Case Studies

Harnessing physics and AI to unlock complex dynamics of challenging targets and accelerate early discovery of small molecules, (macrocyclic) peptides and novel conjugates.

Case Studies

February 26, 2025

Predict ADC Linker Cleavage Site

February 26, 2025

Predicting ADC Drug Efflux

February 25, 2025

Boosting Payload Efficacy Through Bystander Killing Effects

January 14, 2025

Lead Optimization

Optimization of Small Molecule Inhibitors against SARM1

January 14, 2025

Lead Optimization

Discovery and Optimization of PLK1 Inhibitors

January 14, 2025

Lead Optimization

Identification of TLR7 Antagonists with Novel Scaffold

January 14, 2025

Membrane Protein

Lead Optimization in the SLC7A11 Membrane Protein System

January 14, 2025

Dual Inhibitors Targeting Nav1.8 and Nav1.7 Channels

January 14, 2025

Allosteric Site

Non-Covalent GPX4 Inhibitors

January 14, 2025

Discovery of Cyclic Peptides Targeting β-Catenin

January 14, 2025

Reinforced Dynamics-Guided Discovery of Small Molecules Targeting Undruggable c-Myc